Kyiv: A Russian drone attack late Wednesday night killed two civilians and injured five others in Odesa, southern Ukraine, officials confirmed on Thursday.

Odesa region governor Oleg Kiper said the strike targeted a residential area and caused damage to several structures, including apartment buildings, individual homes, a supermarket, and a school.

"Fires broke out in some places, which our rescuers are extinguishing," Kiper reported on Telegram.

Odesa Mayor Gennadiy Trukhanov added that emergency and utility services are on site to manage the aftermath and ensure victims receive medical assistance.

The attack on Odesa was part of a broader wave of strikes across Ukraine. Explosions were heard in the city of Sumy, and air raid alerts were activated across multiple regions including Kyiv, Kharkiv, Chernihiv, Donetsk, Dnipropetrovsk and Zaporizhzhia.

The escalation in attacks comes just as the United States and Ukraine signed a new minerals cooperation deal on Wednesday. The Trump administration has presented the accord as a renewed form of strategic support for Ukraine, following its decision to halt military aid.

Initially hesitant, Ukraine eventually agreed to the deal, seeing it as a means to attract long-term American investment in critical minerals and industrial capacity. This shift in US posture marks a notable change in its engagement with Ukraine amid global military realignments.