Joy Mathew was born as the second of the five children of Chalissery Pulikkottil Mathew and Puthoor Maramath Esther. He completed his education from Kozhikode Mathrubandhu Vidyasala, Malabar Christian College, Zamorins Guruvayurappan College, Govt. Arts and Science College and K. C. College Mumbai. He was active in theatre art while he was in school and college. He was selected as the best actor in Calicut University in three years. Joy Mathew also led the Campus Theatre movement in Kerala. He performed the character of ‘Purushan’ in the popular cinema ‘Amma Ariyan’ directed by John Abraham and produced by Odessa.

Joy Mathew produced the telefilm ‘Uyirthezhunnelp’ directed by Syamaprasad, which won four awards of the state government. He is the script writer and director of the movie ‘Shutter’, which won the Silver Pheasant award in the 17th International Film Festival of Kerala and the state government award for the best actress. The world premiere of ‘Shutter’ was held in Dubai, where Joy Mathew had spent about 10 years as an expatriate. The movie was screened at the film festivals of Hamburg, Busan, Pune, Bengaluru and Chennai, and also won the record of being the movie that was dubbed into most number of Indian languages including Tamil, Telugu, Kannada, Konkani, Marathi and Gujarati.

Joy Mathew is the author of about 22 dramas including Shishu, Athirthikal, Madhyadharanyazhi, Sankadal, Veedukal Kathunnu, Pretoria Oct 16, and Rakthathabala, and more than 15 poems and three screenplays. He has won Kerala Sahithya Academy Award twice for play writing (Shishu, Madhyadharanyazhi) and Kerala Sangeetha Nadaka Academy Award (Sankadal) as well. In a span of 4 years, he has acted in about 85 films in Tamil, Telugu and Hindi languages apart from Malayalam. He won Special Jury Award of the state government for his performance in ‘Mohavalayam’ directed by T. V. Chnadran.