Can a root canal treatment reduce blood sugar levels and prevent heart disease? New study suggests yes

If the thought of a root canal makes you anxious, there may be a silver lining. Research from King’s College London indicates that treating tooth infections with a root canal could bring benefits far beyond a healthy smile. The study suggests that addressing dental infections may help reduce the risk of diabetes, improve heart health, and lower inflammation in the body.

What did the study find?

The first-of-its-kind research tracked 65 patients with common tooth infections (apical periodontitis) over two years. After successful root canal treatment, patients showed:

• Lower blood sugar levels: Significant drops in glucose over two years, suggesting protection against type 2 diabetes.
• Improved cholesterol and fats: Short-term improvements in blood lipid levels, linked to heart health.
• Reduced inflammation: Key markers connected to chronic diseases like cardiovascular conditions fell over time.

The study shows that bacteria from infected teeth can enter the bloodstream, triggering inflammation and altering the body’s metabolism. Treating the infection doesn’t just save the tooth—it also supports overall health.

How was the research conducted?

Scientists analysed blood molecules using nuclear magnetic resonance (NMR) spectroscopy, a technique that reveals how the body processes sugar, fat, proteins, and other substances. By monitoring metabolic markers such as glucose, triglycerides, and tryptophan, researchers could assess how patients’ bodies responded to treatment over time.

Who is behind the study?

The research was led by Dr Sadia Niazi, Senior Clinical Lecturer in Endodontology at King’s College London, and conducted with patients from Guy’s and St Thomas’ NHS Foundation Trust. It was published in the Journal of Translational Medicine and funded by the Faculty of Dental Surgery of the Royal College of Surgeons (RCS) England.

Why does it matter?

Globally, untreated oral infections affect billions and can have far-reaching health impacts. Experts say oral health should be considered part of general healthcare. Early dental treatment, regular check-ups, and monitoring blood markers could reduce risks for heart disease, diabetes, and other chronic conditions.

Root canals, often feared for pain and discomfort, may now be recognised not just as a dental procedure but as a step towards protecting long-term health.