Medicines for Asthma, Jaundice can prevent COVID, say Malayalee researchers
Kochi: Some medicines prescribed for asthma and jaundice can prevent COVID-19, according to a study by Malayalee researchers.
A group of researchers in Kannur University and Bengaluru Kristu Jayanti college discovered the fact. Two studies on these findings were published in ‘Journal of Biomolecular Structure and Dynamics', an international science journal.
Coronavirus transmits genetic material to the human body. Soon after this, it multiplies by using the cells. Main Proteus, an enzyme, helps coronavirus for reproduction on human cells. Medicines for Asthma and Hepatitis C can prevent the enzyme from acting on the body, says the study by the researchers.
As the study was based on molecular modelling, further studies should be carried out to confirm whether these medicines are effective in COVID-19 patients.
The study was carried out under Dr C Sadasivan and Dr Jayadevi Warrier from the Biotechnology-Microbiology department in Kannur university. Lecturer Dr Dileep Francis and research scholars Abhithaj, Arun Kumar and Saranya Suresh from Bengaluru Kristu Jayanthi college also took part in the research.
The researchers used the drug repurposing method for the study. It is a strategy for identifying new uses of approved drugs for treating other diseases. Computer models are used for this research method.
Advantages of drug repurposing
Drugs which have completed safety assessment test are used for drug repurposing. Hence, there is no need to complete the formalities of medicine trial to administer these medicines on patients.
Medicines identified effective for COVID-19 through drug repurposing will be made available in the market soon. A clinical trial should be carried to confirm its efficiency in COVID-19 treatment.